MODERN METHODS FOR PREDICTING COGNITIVE DISORDERS IN PARKINSON'S DISEASE

In Parkinson's disease (PD), among the clinical and symptomatic manifestations of the disease in recent years, attention has been increasingly paid to the so-called non-motor symptoms, that is, cognitive disorders. In PD, cognitive disorders can manifest themselves in the form of a decrease in executive, visual, and visuospatial activity and memory impairment from mild to severe dementia. Cognitive impairments of a subjective and objective nature are often found at the level of early and mild manifestations. In such situations, it is important to develop a strategy for predicting the progression of cognitive disorders and developing methods for their prevention. Long-term and multicenter studies conducted over the past 30-40 years have shown that after the diagnosis of PD, dementia develops after ten courses of the underlying disease. This, in turn, aggravates the already complex course of PD with a pronounced decrease in the quality of life of patients.