Induced Resistance of Ocular Surface Flora in Patients Undergoing Cataract Surgery.

Although short-course pre-operative antibiotics reduce ocular surface bacterial growth, they do not eradicate it in the majority of patients. This could explain why topical antibiotics are less effective than intracameral antibiotics. Further, pre-operative antibiotic use may induce antibiotic resistance and may negatively affect the capabilities of intracameral antibiotics in endophthalmitis prevention and treatment.