Mesenchymal Stem Cell Therapy- A Promising Treatment for Wound Healing in Diabetic Patients

Background: Stem cells have been found to accelerate wound closure, promote tissue regeneration, and modulate the inflammatory response in diabetic wounds. Mesenchymal stem cells release growth factors and cytokines that stimulate angiogenesis, collagen synthesis, and the recruitment of immune cells, all essential processes in wound healing. Additionally, they possess immunomodulatory properties, reducing chronic inflammation often seen in diabetic wounds. Method: Published articles from indexed scientific journals on Stem Cell Therapy that were found to be relevant were chosen. The selected papers were analyzed for both quantitative and qualitative information on Stem Cell Therapy for Diabetic Patients. The compiled information was organized in a sequential manner for the understanding of the basics of Stem Cell Therapy in Diabetic Patients. Our research turned up articles considering the benefits and drawbacks of stem cell therapy. Result: Based on the findings of these articles, we would like to add that, although there are still many unanswered questions about long-term safety and standardized protocols, stem cell therapy has enormous potential. Stem cell therapy presents a glimmer of hope for those suffering from non-healing wounds, since it may be able to avoid amputation and enhance overall quality of life. Conclusion: It is possible to enhance wound healing through the application of various stem cell modifications, co-cultures, and scaffolds. Further research is required to ascertain the molecular workings of stem cells and to raise their therapeutic effectiveness inclinical practice.

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Publication Details

Journal
Research Journal of Pharmacy and Technology
Published
2024-12-27
DOI
https://doi.org/10.52711/0974-360x.2024.00917
Primary Topic
Mesenchymal stem cell research
Type
article
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article

Mesenchymal Stem Cell Therapy- A Promising Treatment for Wound Healing in Diabetic Patients

Karthik Nair, Vijaya Paul Samuel, Naveen Kumar, Zaina Nafees et al.
Research Journal of Pharmacy and Technology
Mesenchymal stem cell research
article

Mesenchymal Stem Cell Therapy- A Promising Treatment for Wound Healing in Diabetic Patients

Karthik Nair, Vijaya Paul Samuel, Naveen Kumar, Zaina Nafees, Murk Jaipal Paryani, Uvashree Shrinivas
article en

Abstract

Background: Stem cells have been found to accelerate wound closure, promote tissue regeneration, and modulate the inflammatory response in diabetic wounds. Mesenchymal stem cells release growth factors and cytokines that stimulate angiogenesis, collagen synthesis, and the recruitment of immune cells, all essential processes in wound healing. Additionally, they possess immunomodulatory properties, reducing chronic inflammation often seen in diabetic wounds. Method: Published articles from indexed scientific journals on Stem Cell Therapy that were found to be relevant were chosen. The selected papers were analyzed for both quantitative and qualitative information on Stem Cell Therapy for Diabetic Patients. The compiled information was organized in a sequential manner for the understanding of the basics of Stem Cell Therapy in Diabetic Patients. Our research turned up articles considering the benefits and drawbacks of stem cell therapy. Result: Based on the findings of these articles, we would like to add that, although there are still many unanswered questions about long-term safety and standardized protocols, stem cell therapy has enormous potential. Stem cell therapy presents a glimmer of hope for those suffering from non-healing wounds, since it may be able to avoid amputation and enhance overall quality of life. Conclusion: It is possible to enhance wound healing through the application of various stem cell modifications, co-cultures, and scaffolds. Further research is required to ascertain the molecular workings of stem cells and to raise their therapeutic effectiveness inclinical practice.

Research Journal of Pharmacy and Technology
College of Medical Sciences (NP), Ras al-Khaimah Medical and Health Sciences University (AE)
Openalex Percentile: Top 54%
Mesenchymal stem cell research
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Mesenchymal Stem Cell Therapy- A Promising Treatment for Wound Healing in Diabetic Patients — Karthik Nair, Vijaya Paul Samuel, et al. · Research Journal of Pharmacy and Technology (2024) | TGRS Research Map | TGRS