Uveitis associated with juvenile idiopathic arthritis in children of the Republic of Sakha (Yakutia): epidemiological data and a series of clinical observations

The article presents a comprehensive cohort retrospective study of patients diagnosed with JIA who underwent examination and treatment in the cardiorheumatology department of the Pediatric Center of the Republican Hospital No. 1 – the National Center of Medicine named after M.E. Nikolaev in 2016-2023. Patients who have developed uveitis have been selected for a detailed analysis. The prevalence of uveitis in the RS(I) was 8.6 per 100,000 children, of which 11.8 among Sakha children and 5.6 among Russians. Uveitis among children with JIA is more common in boys of Sakha nationality, and is more common in older children without correlation with types of JIA. Low efficacy of initial methotrexate therapy has been demonstrated. All cases of de novo uveitis have been recorded only in children of Sakha nationality, most of whom are boys. Keywords: uveitis, juvenile idiopathic arthritis, children, Russians, Sakha, Yakutia.