MICROFLUIDICS AS AN ALTERNATIVE METHOD OF SPERM PROCESSING TO IMPROVE ASSISTED REPRODUCTIVE TECHNOLOGIES (ART) OUTCOMES

An important stage in the development of assisted reproductive technologies (ART) is the introduction of new methods for both fertilization and sperm selection into clinical practice. This article presents a comparative analysis of IVF/ICSI protocols using different sperm selection technologies. The clinical outcomes of cycles employing gradient centrifugation method (GCM), vertical microfluidics method (MVM) using the microfluidic chip Fertile Plus, and horizontal microfluidics method (MHM) were evaluated based on fertilization rates, quality, and quantity of embryos by the fifth day of cultivation. Additionally, data on implantation rates and pregnancy rates were utilized. This research is being conducted for the first time in the Republic of Belarus.