To compare the effects of early Mobilization VS Thrombolytics in Prevention of Venous Thromboembolism after Knee and Hip Arthroplasty

Objective: To compare the effects of early mobilization versus thrombolytics in prevention of venous thromboembolism after knee and hip arthroplasty. Study Design: Randomized control experiment. Place and Duration: The study was conducted at Pakistan Atomic Energy Commission Hospital Islamabad for One year from 10th June 2021 to 30th July 2022. Methodology: Two groups of forty-eight knee and hip arthroplasty patients were purposefully selected and assigned to a one-year randomized control experiment at Pakistan Atomic Energy Commission Hospital Islamabad. For one week, Group A (early mobilization) performed ankle pumping exercises three times a day, while Group B (thrombolytic) took thrombolytics for three weeks. Screening for inclusion criteria was done, and data was gathered and evaluated using Well’s score. SPSS V 26 was used for analysis, with the independent sample t test being used to test for intergroup differences and the Shapiro-Wilk test for data normality. Results: The results showed that there was statistically significant difference between two groups with p < 0.05. Pre-treatment Mean ±SD of well’s score in early mobilization is 1.6250±0.64 while in thrombolytics is 1.7917±0.83. The results showed statistically significant difference for both groups (p-value <0.05) with greater difference seen in early mobilization group. Conclusion: Study concluded that both techniques were effective with more effectiveness of early mobilization in patients of hip and knee arthroplasty. Keywords: Arthroplasty, Early Mobilization, Thrombolytic, Venous Thromboembolism, Prophylaxis, Anticoagulants. How to Cite This: Ghouri QM, Mustafa S, Khalid MN, Janjua SN, Munawar S, Shaheen U. To compare the effects of early Mobilization VS Thrombolytics in Prevention of Venous Thromboembolism after Knee and Hip Arthroplasty. Isra Med J. 2024; 16(2): 47-51. DOI: https://doi.org/10.55282/imj.oa1418.