Effects of Whole Blood Storage on Hematological Parameters of Sudanese Donors attending Central Blood Bank

Background: During storage of blood several hematological and biochemical changes take place that may affect viability of blood cells and other components. In Sudan (to our knowledge) there is no enough information about these changes and there are some gaps in the studies that have been conducted, it did not include all hematological parameters, thus the aim of the present study is to study the various hematological changes occurring in stored whole blood. Methods: This is cross-sectional study conducted at Central Blood Bank, Khartoum state. The study conducted in the period from October 2019 to February 2020, included 100 Sudanese adults donors at defined age group (18-48). The Complete Blood Count (CBC) was performed on it immediately at the time of collection, and this was considered as control, then CBC performed at 1,2,3,4 weeks using automated cell count (Sysmex KY21N). Results: In the first and second weeks there were insignificant changes in all hematological parameters except for platelets, there was a significant decrease started from first week (2.086 vs 3.286; p value =.005) compared to the control, while in third and fourth weeks all changes that occurred with a significant decrease, except for the MCV, which was significant increase in fourth week (90.725 vs. 87.846; p value =.001) compared to the control. Conclusions: All hematological parameters that evaluated above affected by storage, but platelets are more affected which have significant decrease in Day 7.