CLINICAL AND INSTRUMENTAL MARKERS OF COMPLICATED COURSE OF INFECTIOUS-INFLAMMATORY DISEASES IN EXTREMELY PREMATURE NEWBORNS

The study evaluated clinical parameters of 74 premature newborns, as well as the results of laboratory and instrumental methods for diagnosing congenital infection. Statistically significant differences between groups were found in gestational age, birth weight, Apgar score, and results of laboratory and instrumental studies, including platelet levels and markers of inflammation. When assessing diagnostic accuracy, interleukin-6 had the most pronounced 351 diagnostic value on the 1st day, and procalcitonin on the 3rd-5th days. Brain neurosonography revealed more frequent periventricular edema and morphological changes in Group 1. Abdominal ultrasound also showed more frequent visible pathology in Group 1.