Features of endocrinology status at acne for the women of early reproductive age

The objective: to learn endocrinology aspects acne for the women of early reproductive age. Materials and methods. As a result of screening inspection in research 50 patients entered from acne different degree of severity. All patients produced complaints on acne in the area of person, and 10 women (20,0%) also and in the area of breasts and back. Rashes, as a rule, were not accompanied by the subjective feelings, after a liquid exception, when separate elements were sickly at palpation. In addition, 39 patients (78,0%) marked the enhanceable facial skin greasiness and scalp. Age of the investigated patients ranges from 18 to 25 years. To the complex of the conducted researches clinical, laboratory, instrumental and statistical methods were included. Determination in plasma of blood of albuminous (follicle-stimulating hormone, luteinizing hormone) and steroid hormones (estradiol, testosterone, progesterone and dehydroepiandrosterone sulfate) was conducted by radioimmunological methods in the first phase of menstrual cycle on 5-8 day to treatment and in 6 months from the beginning of researchResults. Changes of hormonal type in blood of patients from acne allowed to establish the phenomenon of hyperandrogenism, however much the analysis of changes of level of hormones presents possible with authenticity to define the form of hyperandrogenic changes. Exact information in relation to the exposure of predominating role of ovaries, adrenal glands or hypothalamus, and also possibility of presence of different forms of hyperandrogenism can be got only at the analysis of steroid type of urine, which was conducted before the beginning of treatment to the patients for the rational selection of system therapy with the use of hormonal preparations.Conclusions. The results of the conducted researches testify that findings must be taken into account at development of algorithm of diagnostic and treatment-and-prophylactic measures, especially directed hormonal correction. Keywords:acne, clinical aspects, endocrinology status, early reproductive age.