Tactile edges and motion via patterned microstimulation of the human somatosensory cortex
Intracortical microstimulation (ICMS) of somatosensory cortex evokes tactile sensations whose properties can be systematically manipulated by varying stimulation parameters. However, ICMS currently provides an imperfect sense of touch, limiting manual dexterity and tactile experience. Leveraging our understanding of how tactile features are encoded in the primary somatosensory cortex (S1), we sought to inform individuals with paralysis about local geometry and apparent motion of objects on their skin. We simultaneously delivered ICMS through electrodes with spatially patterned projected fields (PFs), evoking sensations of edges. We then created complex PFs that encode arbitrary tactile shapes and skin indentation patterns. By delivering spatiotemporally patterned ICMS, we evoked sensation of motion across the skin, the speed and direction of which could be controlled. Thus, we improved individuals' tactile experience and use of brain-controlled bionic hands.
Authors
- Nicholas G. Hatsopoulos (ORCID: https://orcid.org/0000-0002-4913-6051)
- Jennifer L. Collinger (ORCID: https://orcid.org/0000-0002-4517-5395)
- Dillan Prasad (ORCID: https://orcid.org/0000-0002-2161-3282)
- Sliman J. Bensmaı̈a (ORCID: https://orcid.org/0000-0003-4039-9135)
- Michael L. Boninger (ORCID: https://orcid.org/0000-0001-6966-919X)
- Charles M. Greenspon (ORCID: https://orcid.org/0000-0002-6806-3302)
- Giacomo Valle (ORCID: https://orcid.org/0000-0002-2637-8007)
- Anton R. Sobinov (ORCID: https://orcid.org/0000-0003-0513-9194)
- Lee E. Miller (ORCID: https://orcid.org/0000-0001-8675-7140)
- Peter C. Warnke (ORCID: https://orcid.org/0000-0001-7989-5692)
- John E. Downey (ORCID: https://orcid.org/0000-0002-2992-2848)
- Robert A. Gaunt (ORCID: https://orcid.org/0000-0001-6202-5818)
- Robin Lienkämper (ORCID: https://orcid.org/0000-0002-2136-4669)
- Linnea J. Endsley
- Patrick M. Jordan
- Ali H. Alamri (ORCID: https://orcid.org/0000-0002-0997-1810)
Institutions
- Northwestern University (US)
- Shirley Ryan AbilityLab (US)
- University of Pittsburgh (US)
- University of Chicago (US)
- Neurological Surgery (US)
- Chalmers University of Technology (SE)
Publication Details
- Journal
- Science
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1126/science.adq5978
- Citations
- 41
- Primary Topic
- Tactile and Sensory Interactions
- Type
- article
- Field-Weighted Citation Impact
- 58.68
Funders
- National Institutes of Health