Interpreting positive celiac serology in children with new-onset type 1 diabetes
Early celiac screening in T1DM is reliable and promotes timely CD diagnosis and treatment. Although transient positive celiac serologies were noted, the degree of TTG-IgA elevation and EMA positivity are strong predictors of coexisting CD. Larger prospective studies using these assays will further define the risk stratification algorithm that is needed for our T1DM community.
Authors
- Steven M. Willi
- Arunjot Singh (ORCID: https://orcid.org/0000-0003-3642-0827)
- Colin P. Hawkes (ORCID: https://orcid.org/0000-0001-6484-0445)
- SANDO OJUKWU
- Paige Coughlin
- Lydia Ramharack
- Lionola Juste
Institutions
- Joslin Diabetes Center (US)
- Children's Hospital of Philadelphia (US)
- University College Cork (IE)
- Infant (IE)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1515/jpem-2024-0070
- Citations
- 1
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.81