Lupus vulgaris over the earlobe with atypical milia formation

We report a case of a 69-year-old woman with recurrent reddish-brown plaques over the left auricle with milia formation. Diascopy showed an ‘apple jelly’ appearance. Histopathology revealed inflammatory epithelioid granulomas with mild central caseous necrosis. A QuantiFERON TB Gold test, staining for acid-fast bacillus and tissue culture, were negative, and the Mantoux test was weakly positive. The diagnosis of lupus vulgaris was based on a positive polymerase chain reaction for Mycobacterium tuberculosis DNA in both lesions. A triad antitubercular therapy was introduced and the patient’s lesions completely resolved within 6 months, with transient increased milia formation over the lesions.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2025-01-16
DOI
https://doi.org/10.1093/ced/llaf029
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Lupus vulgaris over the earlobe with atypical milia formation

Xiaoqing Zhao, Huiyi Ke, Jingying Wang, Meng Pan
Clinical and Experimental Dermatology
Nail Diseases and Treatments
article

Lupus vulgaris over the earlobe with atypical milia formation

Xiaoqing Zhao, Huiyi Ke, Jingying Wang, Meng Pan
article en

Abstract

We report a case of a 69-year-old woman with recurrent reddish-brown plaques over the left auricle with milia formation. Diascopy showed an ‘apple jelly’ appearance. Histopathology revealed inflammatory epithelioid granulomas with mild central caseous necrosis. A QuantiFERON TB Gold test, staining for acid-fast bacillus and tissue culture, were negative, and the Mantoux test was weakly positive. The diagnosis of lupus vulgaris was based on a positive polymerase chain reaction for Mycobacterium tuberculosis DNA in both lesions. A triad antitubercular therapy was introduced and the patient’s lesions completely resolved within 6 months, with transient increased milia formation over the lesions.

Clinical and Experimental DermatologyVol. 50(6)
Shanghai Jiao Tong University (CN), Ruijin Hospital (CN)
Openalex Percentile: Top 99%
Nail Diseases and Treatments
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