Improving the Therapeutic Efficacy of Felbinac: A Nano Carrier-Based Transdermal Delivery System

Nowadays, TDDS is a propitious approach for developing a formulation with enhanced permeation, reduced gastrointestinal side effects, and improved patient compliance. There are several ways to enhance transdermal permeation, in which the incorporation of nano lipid carriers like transferosomes; is observed as an efficient method for the delivery of drug candidates transdermally. Felbinac has promising action in treating severe pain, inflammation, and rheumatoid arthritis. The present study is based on crafting a transferosomal patch of felbinac aiming to enhance transdermal permeation and improve efficacy to get better patient compliance. The transdermal patch is evaluated for different quality attributes. A significant enhancement in drug permeation was observed. This shows a ray of hope towards developing an effective transdermal formulation.