Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study

The administration of IVIG was associated with a reduction in sepsis mortality and favorable outcomes in laboratory parameters and the functional status. These results will contribute to the ongoing debate on the efficacy of IVIG for sepsis. The results obtained herein suggest the benefit of IVIG, particularly in mitigating PICS. Further research, including prospective studies, is warranted to confirm these results and examine long-term outcomes.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-01-16
DOI
https://doi.org/10.3389/fimmu.2024.1511481
Citations
1
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
1.55

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article

Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study

Hiroyuki Ohbe, Yuji Wakimoto, Kensuke Nakamura, Hayabusa Takano et al.
1 citations
Frontiers in Immunology
Intensive Care Unit Cognitive Disorders
1.55
article

Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study

Hiroyuki Ohbe, Yuji Wakimoto, Kensuke Nakamura, Hayabusa Takano, Naoki Kanda
article en
1 citations

Abstract

The administration of IVIG was associated with a reduction in sepsis mortality and favorable outcomes in laboratory parameters and the functional status. These results will contribute to the ongoing debate on the efficacy of IVIG for sepsis. The results obtained herein suggest the benefit of IVIG, particularly in mitigating PICS. Further research, including prospective studies, is warranted to confirm these results and examine long-term outcomes.

Frontiers in ImmunologyVol. 15
Jichi Medical University (JP), Tohoku University Hospital (JP), Yokohama City University Hospital (JP), Showa General Hospital (JP), Hitachi General Hospital (JP), Yokohama City University (JP)
Japan Blood Products Organization
Openalex Percentile: Top 24%
Intensive Care Unit Cognitive Disorders
1.55
DOIOpen Access PDFOpenAlex
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Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study — Hiroyuki Ohbe, Yuji Wakimoto, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS