Long-term disease control in dedifferentiated liposarcoma: a case report on trabectedin priming followed by PD-1 inhibition
This report provides exemplary insight on the feasibility and efficacy of sequential pre-treatment with trabectedin as a priming strategy for PD-1 inhibition in advanced DDLPS. Full trial results from NitraSarc are pending for publication.
Authors
- Christoph K. W. Deinzer
- Peter Raab
- Marcus Zimmermann
- Johan Friso Lock (ORCID: https://orcid.org/0000-0002-9007-3937)
- Lukas Haug (ORCID: https://orcid.org/0009-0008-8714-327X)
- Andreas Rosenwald (ORCID: https://orcid.org/0000-0001-7282-8374)
- Maximilian Rudert (ORCID: https://orcid.org/0000-0003-4982-6594)
- Daniel Pink (ORCID: https://orcid.org/0000-0001-7243-7373)
- Christine Riedhammer (ORCID: https://orcid.org/0009-0008-7106-7217)
- Anne Hendricks
- Peter Reichardt (ORCID: https://orcid.org/0009-0008-1410-3111)
- Armin Wiegering (ORCID: https://orcid.org/0000-0001-7777-0909)
- Viktoria Buck (ORCID: https://orcid.org/0000-0001-6123-1599)
- K. Martin Kortüm (ORCID: https://orcid.org/0000-0002-7011-0286)
- Anke Heidemeier (ORCID: https://orcid.org/0000-0001-8436-4116)
- Volker Kunzmann (ORCID: https://orcid.org/0000-0002-3615-7566)
- Hermann Einsele
- Johannes M. Waldschmidt (ORCID: https://orcid.org/0000-0001-5340-1818)
Institutions
- University of Würzburg (DE)
- Universitätsmedizin Greifswald (DE)
- Comprehensive Cancer Center Mainfranken (DE)
- Klinik König-Ludwig Haus (DE)
- Helios Hospital Bad Saarow (DE)
- University Children's Hospital Tübingen (DE)
- Universitätsklinikum Würzburg (DE)
- Helios Hospital Berlin-Buch (DE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3389/fonc.2024.1518775
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Julius-Maximilians-Universität Würzburg
- PharmaMar