Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study
This large case-control study confirmed established risk factors of dementia. In addition, the study identified non-specific diagnoses that showed a steep increase in risk close to the index date, such as psychosis, conduct disorder, and other sensory disorders. Consideration of these diagnoses, which may represent prodromal features rather than risk factors for dementia, may help to identify people with dementia in routine care.
Authors
- Stefan Teipel (ORCID: https://orcid.org/0000-0002-3586-3194)
- Jens Bohlken
- Steffi Gerlinde Riedel-Heller (ORCID: https://orcid.org/0000-0003-4321-6090)
- Manas K. Akmatov (ORCID: https://orcid.org/0000-0003-2310-3179)
- Jakob Holstiege (ORCID: https://orcid.org/0000-0003-1337-6640)
- Bernhard Michalowsky
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Rostocker Zentrum zur Erforschung des Demografischen Wandels (DE)
- University of Rostock (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1186/s13195-024-01662-x
- Citations
- 6
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 8.83