Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study
Our results indicate that the multiplex ddPCR is a promising platform as a complementary add-on to conventional BC. The DNA loads of <i>E. coli</i> and <i>K. pneumoniae</i> present excellent predictive value for the corresponding BSIs. Further research is needed to explore the predictive potential of ddPCR for other microorganisms.
Authors
- Kang Liao
- Pingjuan Liu (ORCID: https://orcid.org/0000-0001-8824-5851)
- Jiankai Deng
- Yaqin Peng (ORCID: https://orcid.org/0000-0003-3094-1701)
- Bin Huang (ORCID: https://orcid.org/0000-0001-8769-7979)
- Penghao Guo (ORCID: https://orcid.org/0000-0002-9473-7649)
- Ruijie Xie (ORCID: https://orcid.org/0000-0002-1635-962X)
- Yili Chen (ORCID: https://orcid.org/0000-0002-1409-631X)
- Yifeng Luo (ORCID: https://orcid.org/0000-0001-8528-0942)
- Zhongwen Wu (ORCID: https://orcid.org/0000-0002-4700-5605)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3389/fcimb.2024.1489792
- Citations
- 8
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 10.55