Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology
The study highlights the potential of VirB proteins as novel diagnostic antigens for human brucellosis. Future research can further optimize the use of VirB proteins in diagnostic assays and explore their applications in vaccine development.
Authors
- Liping Guo (ORCID: https://orcid.org/0000-0002-3393-4972)
- Jinpeng Zhang (ORCID: https://orcid.org/0000-0002-4264-9583)
- Dehui Yin (ORCID: https://orcid.org/0000-0002-7164-9320)
- Qi Wu (ORCID: https://orcid.org/0000-0003-3562-6129)
- Chen Sun (ORCID: https://orcid.org/0009-0003-1282-3661)
- Y. G. Xie (ORCID: https://orcid.org/0009-0006-3489-5879)
Institutions
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3389/fcimb.2024.1514046
- Citations
- 4
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.42
Funders
- Jiangsu Commission of Health
- Government of Jiangsu Province
- Xuzhou Science and Technology Bureau