GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis
Our study indicates that GPR55 in TME cells may drive tumor growth by suppressing T cell functions, such as migration, in a model of PDAC, making it an interesting target for immunotherapies.
Authors
- Rudolf Schicho (ORCID: https://orcid.org/0000-0002-5726-4731)
- Arailym Sarsembayeva (ORCID: https://orcid.org/0000-0001-9793-0789)
- Dušica Ristić
- Julia Kargl (ORCID: https://orcid.org/0000-0002-0870-0816)
- Karolina Herceg (ORCID: https://orcid.org/0000-0002-3450-4296)
- Thomas Bärnthaler (ORCID: https://orcid.org/0000-0002-4988-3700)
- Melanie Kienzl (ORCID: https://orcid.org/0000-0001-6508-176X)
- Eva Gruden
- Laura Danner
Institutions
- Medical University of Graz (AT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3389/fimmu.2024.1513547
- Citations
- 2
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Austrian Science Fund
- Karl-Franzens-Universität Graz
- Medizinische Universität Graz