Skullcapflavone II suppresses TGF-β-induced corneal epithelial mesenchymal transition in vitro
SCF-II inhibit TGF-β-induced EMT in HCECs by potentially regulating the NF-κB signalling pathway. Thus, SCF-II represents a candidate putative therapeutic agent in corneal fibrotic diseases.
Authors
- Fangyu Zhao (ORCID: https://orcid.org/0000-0002-4191-7355)
- Yangyang Yue (ORCID: https://orcid.org/0000-0003-4281-5534)
- Yufan Li (ORCID: https://orcid.org/0000-0003-3595-9089)
- Yue Zhang (ORCID: https://orcid.org/0000-0003-3568-0395)
- Li Li (ORCID: https://orcid.org/0000-0001-6682-6401)
- Yonghong Dang (ORCID: https://orcid.org/0000-0002-3113-1295)
- Mengxi Li (ORCID: https://orcid.org/0000-0003-4277-949X)
Institutions
- Northwestern Polytechnical University (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.18240/ijo.2025.02.02
- Citations
- 1
- Primary Topic
- Biological Activity of Diterpenoids and Biflavonoids
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Wenzhou Medical University