Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

Authors

Jihui Chen (ORCID: https://orcid.org/0000-0002-9819-9921)
Wenting Hu (ORCID: https://orcid.org/0000-0003-4639-9056)
Yanjing Tang
Yixiao Mo (ORCID: https://orcid.org/0000-0002-5624-2362)
Qi Zhang (ORCID: https://orcid.org/0000-0002-7918-8952)
Jingjing Wang (ORCID: https://orcid.org/0000-0002-9287-0577)
Zhuo Wang (ORCID: https://orcid.org/0000-0002-6382-1717)
Xiaoxiao Chen (ORCID: https://orcid.org/0000-0003-3907-8465)
Changcheng Chen (ORCID: https://orcid.org/0000-0002-5685-203X)
Shuhong Shen
Miao Wang (ORCID: https://orcid.org/0000-0003-0802-996X)

Institutions

Henan University (CN)
Shanghai Jiao Tong University (CN)
XinHua Hospital (CN)
Zhengzhou University (CN)
Shanghai Children's Medical Center (CN)
Henan Provincial People's Hospital (CN)

Publication Details

Journal: Haematologica
Published: 2025-01-16
DOI: https://doi.org/10.3324/haematol.2024.286882
Primary Topic: Acute Lymphoblastic Leukemia research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
Shanghai Municipal Education Commission

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article

Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

Jihui Chen, Wenting Hu, Yanjing Tang, Yixiao Mo et al.

Jan 16, 2025

Haematologica

Acute Lymphoblastic Leukemia research

article

Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia

Jihui Chen, Wenting Hu, Yanjing Tang, Yixiao Mo, Qi Zhang, Jingjing Wang, Zhuo Wang, Xiaoxiao Chen, Changcheng Chen, Shuhong Shen, Miao Wang

January 16, 2025article en

Abstract

No abstract available for this paper.

HaematologicaVol. 110(7)

Henan University (CN), Shanghai Jiao Tong University (CN), XinHua Hospital (CN), Zhengzhou University (CN), Shanghai Children's Medical Center (CN), Henan Provincial People's Hospital (CN)

National Natural Science Foundation of China, Shanghai Municipal Education Commission

Openalex Percentile: Top 99%

Acute Lymphoblastic Leukemia research

DOI Open Access PDF OpenAlex

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Results from patient-derived xenograft models support co-administration of allopurinol and 6-mercaptopurine to reduce hepatotoxicity and improve event-free survival in pediatric acute lymphoblastic leukemia — Jihui Chen, Wenting Hu, et al. · Haematologica (2025) | TGRS Research Map | TGRS