Fatal Serratia Marcescens Necrotizing Fasciitis in an Immunocompetent Man

Necrotizing fasciitis is a difficult-to-treat, life-threatening infection that affects the superficial fascia and the subcutaneous tissue, causing gradual tissue necrosis, often due to a combination of aerobic and anaerobic bacteria.We describe the case of a 57-year-old immunocompetent man who presented with pain in his left leg, local oedema, and dyspnoea.Clinical examination and subsequent histopathological findings were consistent with the diagnosis of necrotizing fasciitis.Tissue biopsies and blood cultures demonstrated the presence of Serratia marcescens.Adequate antibiotic treatment and rapid surgical debridement were accomplished.Despite intensive and aggressive treatments, the patient quickly developed refractory multiple organ failure leading to death.To the best of our knowledge, this is the first fatal case of S. marcescens related necrotizing fasciitis in an immunocompetent man.The patient's fulminant evolution contributes to the uniqueness of this case.