Ag85B-induced M1 Macrophage Polarization via the TLR4/TRAF6/NF-κB Axis Leading to Bronchial Epithelial Cell Damage and TH17/Treg Imbalance
Ag85B promoted M1 polarization in macrophages through the TLR4/TRAF6/NF-κB axis, resulting in bronchial epithelial cell damage and an imbalance in TH17/Treg cells.
Authors
- Yan Ding (ORCID: https://orcid.org/0000-0002-4269-9476)
- Hailong Luo (ORCID: https://orcid.org/0000-0003-1336-8755)
- Linzi Luo
- Li Luo (ORCID: https://orcid.org/0000-0002-9900-5885)
- Lei Zhou (ORCID: https://orcid.org/0000-0003-4615-645X)
- Zhibin Lu (ORCID: https://orcid.org/0000-0003-0548-0325)
- Yangbao Xiao
Institutions
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Hunan Province Chest Hospital (CN)
Publication Details
- Journal
- Current Molecular Medicine
- Published
- 2025-01-16
- DOI
- https://doi.org/10.2174/0115665240319773241204073135
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80