Mucus Plug Score Predicts Clinical and Pulmonary Function Response to Biologic Therapy in Patients With Severe Asthma
Our study suggests that a higher MPS correlates with worse pulmonary function at baseline but also predicts a larger clinical and pulmonary function response to biologic therapies in severe asthma.
Authors
- Julia Walter (ORCID: https://orcid.org/0000-0003-4304-6159)
- Jürgen Behr (ORCID: https://orcid.org/0000-0001-8782-4456)
- Melanie Götschke
- Alexandra Lenoir (ORCID: https://orcid.org/0000-0003-2189-6507)
- Katrin Milger (ORCID: https://orcid.org/0000-0003-2914-8773)
- Gabriela Leuschner (ORCID: https://orcid.org/0000-0002-4717-6922)
- Carlo Mümmler (ORCID: https://orcid.org/0000-0002-2501-3356)
- Nikolaus Kneidinger (ORCID: https://orcid.org/0000-0001-7583-0453)
- Julien Dinkel (ORCID: https://orcid.org/0000-0003-1239-6084)
- Michael Gerckens (ORCID: https://orcid.org/0000-0002-2251-4382)
- Pontus Mertsch (ORCID: https://orcid.org/0000-0002-5032-5941)
- Judith Spiro (ORCID: https://orcid.org/0000-0003-2560-2713)
- Jeremias Götschke (ORCID: https://orcid.org/0000-0002-3426-2194)
- Michaela Barnikel (ORCID: https://orcid.org/0000-0001-6965-0018)
Institutions
- German Center for Lung Research (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- The Journal of Allergy and Clinical Immunology In Practice
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1016/j.jaip.2025.01.010
- Citations
- 17
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 19.79
Funders
- AstraZeneca
- Sanofi