Irisquinone's Anti-cancer Potential: Targeting TrxR to Trigger ROS-mediated Apoptosis and Pyroptosis
Irisquinone showed anticancer activity through inhibiting TrxR. These results suggested that Irisquinone will be developed to be an anti-tumor drug possibility.
Authors
- Guodong Liang (ORCID: https://orcid.org/0000-0002-8850-8663)
- Lu Ga
- Yuheng Ma (ORCID: https://orcid.org/0009-0008-3206-4259)
- Xinyan Wang (ORCID: https://orcid.org/0000-0002-5344-3281)
- Qifeng Zhang (ORCID: https://orcid.org/0000-0002-2742-2188)
- Ren Bu
- Gegen Tana
Institutions
- Inner Mongolia University (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2025-01-16
- DOI
- https://doi.org/10.2174/0118715206339230241202062826
- Citations
- 4
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 7.00