Increased Plasma Pyruvate Kinase M2 (PK‐M2) in Heart Failure: A Novel Biomarker Related to Cardiac Function and its Clinical Implications
Elevated PK-M2 levels are associated with primary outcomes and rehospitalization for worsening heart failure in patients with HF. These findings suggest that PK-M2 is a potential biomarker for HF diagnosis and prognosis, warranting consideration for serial patient assessment.
Authors
- Xiao-yu Dong (ORCID: https://orcid.org/0009-0008-4306-5273)
- Lu Cao (ORCID: https://orcid.org/0000-0001-6644-0963)
- Fuzhong Chen (ORCID: https://orcid.org/0009-0009-5054-0439)
- Junhong Wang (ORCID: https://orcid.org/0000-0003-2314-1810)
- Zhijun Han (ORCID: https://orcid.org/0000-0003-4055-8538)
- Jiang Fang
- Guangjuan Li
Institutions
- Jiangnan University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Yili Friendship Hospital (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1161/jaha.124.036170
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China