Anticancer potential of nerolidol on acute lymphoblastic leukemia cells through the interactions with the NF-κB/STAT-3 and PI3K/Akt signaling pathways

Our results suggest that NRD treatment stimulates apoptosis in MOLT-4 cells by causing the accumulation of intracellular ROS through PI3K/AKT/STAT-3 signaling pathways.

Authors

Hengfei Du
Xuejiao Wang (ORCID: https://orcid.org/0009-0002-1253-5304)
Ke Wang (ORCID: https://orcid.org/0000-0003-2696-2147)

Institutions

China XD Group (China) (CN)

Publication Details

Journal: Advances in Clinical and Experimental Medicine
Published: 2025-01-16
DOI: https://doi.org/10.17219/acem/192695
Primary Topic: Synthesis and biological activity
Type: article
Field-Weighted Citation Impact: 0.00

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article

Anticancer potential of nerolidol on acute lymphoblastic leukemia cells through the interactions with the NF-κB/STAT-3 and PI3K/Akt signaling pathways

Hengfei Du, Xuejiao Wang, Ke Wang

Jan 16, 2025

Advances in Clinical and Experimental Medicine

Synthesis and biological activity

article

Anticancer potential of nerolidol on acute lymphoblastic leukemia cells through the interactions with the NF-κB/STAT-3 and PI3K/Akt signaling pathways

Hengfei Du, Xuejiao Wang, Ke Wang

January 16, 2025article en

Abstract

Our results suggest that NRD treatment stimulates apoptosis in MOLT-4 cells by causing the accumulation of intracellular ROS through PI3K/AKT/STAT-3 signaling pathways.

Advances in Clinical and Experimental MedicineVol. 34(9)

China XD Group (China) (CN)

Openalex Percentile: Top 99%

Synthesis and biological activity

DOI Open Access PDF OpenAlex

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Anticancer potential of nerolidol on acute lymphoblastic leukemia cells through the interactions with the NF-κB/STAT-3 and PI3K/Akt signaling pathways — Hengfei Du, Xuejiao Wang, et al. · Advances in Clinical and Experimental Medicine (2025) | TGRS Research Map | TGRS