Safety and recommendation of voriconazole for invasive pulmonary aspergillosis in severe liver disease patients: a retrospective cohort study

Voriconazole monotherapy demonstrated good tolerability with lower mortality in SLD patients with IPA. A no-loading dose voriconazole regimen is proposed for IPA treatment in SLD patients, yet pharmacokinetic studies combined with prospective studies are needed for further validation.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-01-16
DOI
https://doi.org/10.1186/s12879-025-10459-8
Citations
2
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
2.79
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article

Safety and recommendation of voriconazole for invasive pulmonary aspergillosis in severe liver disease patients: a retrospective cohort study

Xue Chen, Yuqing Sun, Ling Zhang, Yulin Zhang et al.
2 citations
BMC Infectious Diseases
Antifungal resistance and susceptibility
2.79
article

Safety and recommendation of voriconazole for invasive pulmonary aspergillosis in severe liver disease patients: a retrospective cohort study

Xue Chen, Yuqing Sun, Ling Zhang, Yulin Zhang, Caopei Zheng, Lijun Pang, Xin Zhang
article en
2 citations

Abstract

Voriconazole monotherapy demonstrated good tolerability with lower mortality in SLD patients with IPA. A no-loading dose voriconazole regimen is proposed for IPA treatment in SLD patients, yet pharmacokinetic studies combined with prospective studies are needed for further validation.

BMC Infectious DiseasesVol. 25(1)
Capital Medical University (CN), National Clinical Research Center for Digestive Diseases (CN), Beijing YouAn Hospital (CN)
Openalex Percentile: Top 13%
Antifungal resistance and susceptibility
2.79
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