Weight and Blood‐Based Markers of Cachexia Predict Disability, Hospitalization and Worse Survival in Cancer Immunotherapy Patients
Fearon consensus criteria, WLGS, NLR, albumin and PNI were routinely collected at ICI initiation in regular clinical practice and predictive of worse disability-free, hospitalization-free and overall survival in cancer patients receiving ICI therapy. These routine clinical measures may aid prognostication and decision-making in cancer patients with cachexia.
Authors
- Noah Forrest (ORCID: https://orcid.org/0000-0003-4601-7070)
- Giovanni M. Perottino
- Jodi Johnson (ORCID: https://orcid.org/0000-0002-8328-5587)
- Ishan Roy (ORCID: https://orcid.org/0000-0002-9109-0421)
- Jeffrey A. Sosman (ORCID: https://orcid.org/0000-0002-0650-9698)
- Theresa L. Walunas (ORCID: https://orcid.org/0000-0002-7653-3650)
- Steven Tran (ORCID: https://orcid.org/0000-0001-7273-2348)
- Vijeeth Guggilla (ORCID: https://orcid.org/0000-0001-9132-514X)
Institutions
- Northwestern University (US)
- Shirley Ryan AbilityLab (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1002/jcsm.13685
- Citations
- 6
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Northwestern University
- Robert H. Lurie Comprehensive Cancer Center
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- U.S. National Library of Medicine