Therapeutic potential of Curcuma longa against monkeypox: antioxidant, anti-inflammatory, and computational insights
The results demonstrate the multifunctional therapeutic potential of <i>C. longa</i>, driven by its potent antioxidant and anti-inflammatory properties. The computational findings suggest that curcuminoids, particularly demethoxycurcumin, could serve as promising antiviral agents against monkeypox. These findings pave the way for further preclinical studies to validate the antiviral efficacy of <i>C. longa</i> bioactives and their potential applications in combating viral infections.
Authors
- Ahmed Barhoum
- Farouk Boudou (ORCID: https://orcid.org/0000-0002-6008-3325)
- Amal Belakredar (ORCID: https://orcid.org/0000-0003-0997-690X)
- Mikhaël Bechelany (ORCID: https://orcid.org/0000-0002-2913-2846)
- Linda Aissani (ORCID: https://orcid.org/0000-0003-0641-5322)
- Huda Alsaeedi
- Ahcen Keziz
- David Cronu
Institutions
- École Nationale Supérieure de Chimie de Montpellier (FR)
- Centre National de la Recherche Scientifique (FR)
- Université de Mostaganem (DZ)
- Gulf University for Science & Technology (KW)
- Université de Montpellier (FR)
- King Saud University (SA)
- Université Djilali de Sidi Bel Abbès (DZ)
- Abbès Laghrour University of Khenchela (DZ)
- University Mohamed Boudiaf of M'sila (DZ)
- Institut Européen des Membranes (FR)
- Helwan University (EG)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3389/fchem.2024.1509913
- Citations
- 6
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 3.55