SLC2A14 In Hepatoblastoma Clinical Significance And Potential Roles In Ferroptosis
The study aimed to investigate the role of SLC2A14 in hepatoblastomaHB,a prevalent pediatric liver tumor.Through RNA-seq analysis of public and in-house datasets,we found SLC2A14 upregulated in HB and linked to ferroptosis.Our analysis revealed SLC2A14s potential as a diagnostic marker and its association with tumor metabolism,suggesting it may be a therapeutic target.The study concludes that SLC2A14s role in HB should be further explored for clinical applications.
Authors
- Xiang Gao (ORCID: https://orcid.org/0000-0002-3774-1852)
- Guoliang Yan (ORCID: https://orcid.org/0000-0002-4766-0343)
- Jing Li (ORCID: https://orcid.org/0000-0001-7792-4322)
- Jun Liu (ORCID: https://orcid.org/0000-0003-4800-7749)
- Guofang Feng (ORCID: https://orcid.org/0000-0001-7109-1139)
- Wenxia Li (ORCID: https://orcid.org/0009-0009-5223-2341)
- Li Guo (ORCID: https://orcid.org/0000-0003-0330-5865)
- Hua Zhou
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- International Journal of Clinical Medicine and Pharmacology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.70731/m43vmz32
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00