Role of procalcitonin, C-reactive protein and ferritin in cytokine release syndrome after CAR T-cell therapy in children and young adults
PCT levels increase after CAR-T cell therapy in the setting of systemic inflammation and could be a predictor of PICU admission and evolution to death. Further research studying its role in the context of CRS and the differential diagnosis between infection and CRS is needed to better understand the biology of this biomarker and to define its value in clinical practice.
Authors
- Susana Rives (ORCID: https://orcid.org/0000-0002-5658-1831)
- A. Català
- Sara Bobillo‐Pérez (ORCID: https://orcid.org/0000-0001-8889-2995)
- Marina Caballero (ORCID: https://orcid.org/0000-0001-9289-3990)
- Iolanda Jordán (ORCID: https://orcid.org/0000-0002-2041-4425)
- Anna Alonso‐Saladrigues (ORCID: https://orcid.org/0000-0002-3195-5470)
- A. Valls
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- Instituto de Salud Carlos III (ES)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Instituto de Investigación de Enfermedades Raras (ES)
- Institut de Recerca Sant Joan de Déu
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Biomarkers
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1080/1354750x.2025.2454471
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09