Delphi Consensus on the Management of Spanish Patients with Post-Stroke Hemiplegic Shoulder Pain Treated with Botulinum Toxin A: Result Study
The study aimed to identify expert opinions and obtain recommendations on the management of post-stroke hemiplegic shoulder pain (HSP) and treatment with botulinum toxin A (BoNT-A). A multicenter Delphi study was conducted using an online survey designed by a committee of experts with at least 10 years of experience in post-stroke HSP management with BoNT-A in Spain. Forty-seven panelists (specialists with at least 5 years of experience in post-stroke HSP management with BoNT-A) rated their level of agreement in two rounds based on acceptance by ≥66.7% of them. In round 1, 245 statements on three dimensions were evaluated (diagnosis, treatment, and follow-up of the HSP patients treated with BoNT-A). A total of 159 statements (70.9%) were finally accepted after round 2. Experts recommended BoNT-A as soon as spasticity affects daily activities. They considered ultrasound as the preferred guided technique. Experts recommended regular assessments using validated scales and patient-reported outcomes to evaluate treatment goals and safety. In case of lack of response, experts suggested increasing the dose or number of treated muscles or considering alternative treatments. These consensus-based recommendations offer clinicians an approach to the management of post-stroke HSP with BoNT-A, supporting informed decision making.
Authors
- Sergio Otero-Villaverde (ORCID: https://orcid.org/0000-0003-3352-2078)
- Alberto Herrera (ORCID: https://orcid.org/0000-0003-4189-9051)
- Carlos Cordero‐García (ORCID: https://orcid.org/0000-0002-7359-3404)
- Cátia Santa (ORCID: https://orcid.org/0000-0002-7260-4896)
- I. Torres
- J Formigo-Couceiro
- Lluís Guirao (ORCID: https://orcid.org/0000-0002-8698-9483)
- Ma Dolores Romero-Torres (ORCID: https://orcid.org/0000-0003-2370-3887)
- Antonio Mena-Rodriguez
Institutions
- Universidade da Coruña (ES)
- Hospital Universitario Virgen Macarena (ES)
- University Hospital Mútua de Terrassa (ES)
- Hospital Universitario de Gran Canaria Doctor Negrín (ES)
- Ipsen (Spain) (ES)
- Hospital Universitario Reina Sofía (ES)
- Hospital Juan Ramón Jiménez (ES)
Publication Details
- Journal
- Toxins
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3390/toxins17010040
- Citations
- 1
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Ipsen