Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism
In summary, cluster analysis has proved to be a feasible and reliable approach for identifying phenotypic subgroups of calves, prompting further exploration of host-microbiome interactions. Bifidobacterium as a core microbe in the hindgut of calves may play a crucial probiotic role in host phenotypic differentiation. This study enhances our comprehension of how gut core microbe shapes the host phenotype and provides new insights into the manipulation of beneficial gut colonizers to improve the growth performance and productivity of young ruminants. Video Abstract.
Authors
- Guang-Lei Liu (ORCID: https://orcid.org/0000-0002-2551-9170)
- Jingjun Wang (ORCID: https://orcid.org/0000-0002-5262-2157)
- Zhijun Cao (ORCID: https://orcid.org/0000-0002-5519-9462)
- Shuai Liu (ORCID: https://orcid.org/0000-0001-8732-9754)
- Jianxin Xiao (ORCID: https://orcid.org/0000-0002-3074-5973)
- Tianyu Chen (ORCID: https://orcid.org/0000-0002-7616-0874)
- Shangru Li (ORCID: https://orcid.org/0009-0008-2765-0501)
- Duo Gao (ORCID: https://orcid.org/0000-0003-3691-2119)
- Wen Jiang (ORCID: https://orcid.org/0000-0001-9154-633X)
- Siyuan Zhang (ORCID: https://orcid.org/0000-0001-5146-628X)
- Shengli Li (ORCID: https://orcid.org/0000-0002-8494-7474)
- Yiming Xu (ORCID: https://orcid.org/0000-0003-4001-9307)
- Yimin Zhuang
- Mengmeng Li (ORCID: https://orcid.org/0009-0001-3365-8111)
- Guobin Hou
- Wei Wang (ORCID: https://orcid.org/0000-0001-8676-1190)
Institutions
- Xinjiang Agricultural University (CN)
- Sichuan Agricultural University (CN)
- Beijing University of Agriculture (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1186/s40168-024-02010-9
- Citations
- 18
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 14.51
Funders
- National Natural Science Foundation of China
- China Agricultural University
- Key Research and Development Program of Ningxia
- National Postdoctoral Program for Innovative Talents