The KNL-1/Knl1 outer kinetochore protein caught regulating F-actin

Kinetochores are multiprotein complexes that link chromosomes to microtubules and are essential for chromosome segregation during cell divisions. In this issue, Alves Domingos et al. (https://doi.org/10.1083/jcb.202311147) show that the conserved KNL-1/Knl1 protein of the Knl1/Mis12/Ndc80 (KMN) outer kinetochore complex postmitotically regulates F-actin to shape somatosensory dendrites.

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Publication Details

Journal
The Journal of Cell Biology
Published
2025-01-16
DOI
https://doi.org/10.1083/jcb.202412191
Primary Topic
Cellular Mechanics and Interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

The KNL-1/Knl1 outer kinetochore protein caught regulating F-actin

Hannes E. Bülow
The Journal of Cell Biology
Cellular Mechanics and Interactions
article

The KNL-1/Knl1 outer kinetochore protein caught regulating F-actin

Hannes E. Bülow
article en

Abstract

Kinetochores are multiprotein complexes that link chromosomes to microtubules and are essential for chromosome segregation during cell divisions. In this issue, Alves Domingos et al. (https://doi.org/10.1083/jcb.202311147) show that the conserved KNL-1/Knl1 protein of the Knl1/Mis12/Ndc80 (KMN) outer kinetochore complex postmitotically regulates F-actin to shape somatosensory dendrites.

The Journal of Cell BiologyVol. 224(2)
Albert Einstein College of Medicine (US)
National Institutes of Health
Openalex Percentile: Top 99%
Cellular Mechanics and Interactions
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The KNL-1/Knl1 outer kinetochore protein caught regulating F-actin — Hannes E. Bülow · The Journal of Cell Biology (2025) | TGRS Research Map | TGRS