Increased pro-SFTPB in HDL promotes the pro-inflammatory transition of HDL and represents a sign of poor prognosis in ARDS patients
The increase of HDL-pro-SFTPB promotes HDL pro-inflammatory transition during septic ARDS, leading to exacerbated progression of ARDS through enhancing M1 macrophage polarization. HDL-pro-SFTPB could be a useful prognostic biomarker for septic ARDS.
Authors
- Zhipeng Wu (ORCID: https://orcid.org/0000-0002-9889-0798)
- Jing Wang (ORCID: https://orcid.org/0000-0001-5701-476X)
- Jiawei Jin (ORCID: https://orcid.org/0009-0004-2538-2321)
- Fangping Ding
- Zhuo Xu
- Yingmin Ma (ORCID: https://orcid.org/0000-0003-3379-4073)
- Liu Yang (ORCID: https://orcid.org/0000-0001-6848-7669)
- Xiaoqian Shi
- Zhenyan Wang
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1186/s12967-025-06100-6
- Citations
- 2
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 2.59
Funders
- Chinese Academy of Sciences
- Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
- Institute of Genetics