Rapid visual detection of hepatitis E virus combining reverse transcription recombinase-aided amplification with lateral flow dipstick and real-time fluorescence
Hepatitis E virus (HEV) is a globally widespread zoonotic pathogen that poses a significant public health risk. Swine serve as the primary natural host for zoonotic HEV. This study introduces a rapid and precise method for detecting swine HEV RNA, showcasing its potential as an effective diagnostic tool for comprehensive and efficient screening of swine HEV in veterinary clinics.
Authors
- Yanxin Hu (ORCID: https://orcid.org/0000-0001-7009-8451)
- Wenjiao Yin
- Minheng Cheng
- Yifei Yang (ORCID: https://orcid.org/0000-0002-6210-8557)
- Ruiping She (ORCID: https://orcid.org/0000-0002-7604-1680)
- Wenlong Wang (ORCID: https://orcid.org/0000-0002-3355-5438)
- Zhiliang Guo (ORCID: https://orcid.org/0000-0002-9956-1945)
- Tianlong Liu (ORCID: https://orcid.org/0000-0001-7333-9353)
- Yuewei Tian
- Ya‐Xin Sun
- Jijing Tian (ORCID: https://orcid.org/0000-0001-9005-8553)
- Bingyan Wei (ORCID: https://orcid.org/0009-0001-2604-1455)
Institutions
- National Public Health Laboratory (NP)
- Taiwan Centers for Disease Control (TW)
- National Institute for Viral Disease Control and Prevention (CN)
- Beijing Center for Disease Prevention and Control (CN)
- China Agricultural University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Clinical Microbiology
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1128/jcm.01064-24
- Citations
- 5
- Primary Topic
- Hepatitis Viruses Studies and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 6.61
Funders
- National Natural Science Foundation of China
- China Agricultural University