Estimation of the relationship between the blood serum concentrations of selenium, zinc, vitamins C and D, and some of the immunological parameters in healthy people

Aims: This study aims to find out the concentrations of Vitamin C and D, selenium and zinc in the serum of healthy people.Moreover, the study aims to determine IgG and IgM in the individuals under study.Methodology and results: 76 samples were collected from healthy people in Nineveh, including 37 males and 39 females aged 15-59.Information was recorded for each person (gender, age, type's chronic disease, infected with COVID-19).ELISA was used to detect levels of vitamins (C and D) and selenium.The decline in Vitamin D levels in the body had a detrimental influence on the IgM level, which averaged 124.13 mg/dI and the WBC count, which averaged 6.04 10 9 /L.The numbers of lymphocytes and granulocytes averaged 1.95 10 9 /L and 3.93 10 9 /L, respectively, as well as their negative impact on the completion rate, which reached 14.19%.The drop in vitamin C levels in the body had a detrimental effect on both IgG and IgM levels, which reached 591.62 mg/dl and 111.52 mg/dl, respectively.The WBC count averaged 5.97 10 9 /L, as did the number of lymphocytes and granulocytes.They averaged 3.62 10 9 /L and 1.81 10 9 /L, respectively.An increase in zinc levels in the body had a detrimental influence on both IgG and IgM levels, which averaged 633.8 mg/dl and 114.79 mg/dl, respectively.The complement rate was 13.3%.Furthermore, the increase in selenium in the body had a strong detrimental impact on the complement rate, which reached 13.16%.Selenium content had no discernible influence on the other immunological variables studied. Conclusion, significance and impact of study:The low level of vitamin C had an apparent effect on all studied factors.In contrast, the effect of vitamin D and zinc appeared less effective, and selenium had the slightest effect on healthy people.