PSMA+ Extracellular Vesicles Are a Biomarker for SABR in Oligorecurrent Prostate Cancer: Analysis from the STOMP-like and ORIOLE Trial Cohorts

PSMA+EV is a novel prognostic and predictive biomarker of radiographically occult tumor burden in omCSPC. PSMA+EV may inform clinical decisions about identifying patients who will achieve a durable benefit from consolidative SABR alone.

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Publication Details

Journal
Clinical Cancer Research
Published
2025-01-16
DOI
https://doi.org/10.1158/1078-0432.ccr-24-3027
Citations
13
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
19.74
Controls
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article

PSMA+ Extracellular Vesicles Are a Biomarker for SABR in Oligorecurrent Prostate Cancer: Analysis from the STOMP-like and ORIOLE Trial Cohorts

Jack R. Andrews, Sean S. Park, Jacob J. Orme, Philip Anthony Sutera et al.
13 citations
Clinical Cancer Research
Prostate Cancer Treatment and Research
19.74
article

PSMA+ Extracellular Vesicles Are a Biomarker for SABR in Oligorecurrent Prostate Cancer: Analysis from the STOMP-like and ORIOLE Trial Cohorts

Jack R. Andrews, Sean S. Park, Jacob J. Orme, Philip Anthony Sutera, Ryan Phillips, Daniel S. Childs, Carole Mercier, Ali Arafa, Aurélie De Bruycker, Edlira Horjeti, Daniel Y. Song, Yohan Kim, Aadel A. Chaudhuri, Phuoc T. Tran, Ana P. Kiess, Oliver A. Sartor, Piet Ost, Fabrice Lucien, Heather Gunn
article en
13 citations

Abstract

PSMA+EV is a novel prognostic and predictive biomarker of radiographically occult tumor burden in omCSPC. PSMA+EV may inform clinical decisions about identifying patients who will achieve a durable benefit from consolidative SABR alone.

Clinical Cancer ResearchVol. 31(6)
University of Maryland, Baltimore (US), University of Minnesota (US), Mayo Clinic (US), University of Maryland Medical System (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), AZ Groeninge (BE), University of Minnesota System (US), Ghent University Hospital (BE), WinnMed (US), Ghent University (BE), Antwerp University Hospital (BE), Phoenix (United States) (US), Mayo Clinic in Arizona (US), Iridium Kankernetwerk (BE), Mayo Clinic in Florida (US), Johns Hopkins Hospital (US), University of Maryland, College Park (US)
Openalex Percentile: Top 1%
Prostate Cancer Treatment and Research
19.74
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