PSMA+ Extracellular Vesicles Are a Biomarker for SABR in Oligorecurrent Prostate Cancer: Analysis from the STOMP-like and ORIOLE Trial Cohorts
PSMA+EV is a novel prognostic and predictive biomarker of radiographically occult tumor burden in omCSPC. PSMA+EV may inform clinical decisions about identifying patients who will achieve a durable benefit from consolidative SABR alone.
Authors
- Jack R. Andrews (ORCID: https://orcid.org/0000-0002-7781-3638)
- Sean S. Park (ORCID: https://orcid.org/0000-0003-3814-853X)
- Jacob J. Orme (ORCID: https://orcid.org/0000-0002-0319-0239)
- Philip Anthony Sutera (ORCID: https://orcid.org/0000-0002-4021-5909)
- Ryan Phillips
- Daniel S. Childs (ORCID: https://orcid.org/0000-0001-7643-2836)
- Carole Mercier (ORCID: https://orcid.org/0000-0002-0427-8371)
- Ali Arafa
- Aurélie De Bruycker (ORCID: https://orcid.org/0000-0002-3583-481X)
- Edlira Horjeti (ORCID: https://orcid.org/0000-0002-4488-4819)
- Daniel Y. Song (ORCID: https://orcid.org/0000-0002-3495-8677)
- Yohan Kim (ORCID: https://orcid.org/0000-0002-2378-0068)
- Aadel A. Chaudhuri (ORCID: https://orcid.org/0000-0003-3115-3061)
- Phuoc T. Tran (ORCID: https://orcid.org/0000-0002-0147-0376)
- Ana P. Kiess (ORCID: https://orcid.org/0000-0001-6928-3852)
- Oliver A. Sartor (ORCID: https://orcid.org/0000-0002-8777-7343)
- Piet Ost (ORCID: https://orcid.org/0000-0002-2203-4848)
- Fabrice Lucien (ORCID: https://orcid.org/0000-0001-6149-345X)
- Heather Gunn (ORCID: https://orcid.org/0000-0001-8665-2867)
Institutions
- University of Maryland, Baltimore (US)
- University of Minnesota (US)
- Mayo Clinic (US)
- University of Maryland Medical System (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- AZ Groeninge (BE)
- University of Minnesota System (US)
- Ghent University Hospital (BE)
- WinnMed (US)
- Ghent University (BE)
- Antwerp University Hospital (BE)
- Phoenix (United States) (US)
- Mayo Clinic in Arizona (US)
- Iridium Kankernetwerk (BE)
- Mayo Clinic in Florida (US)
- Johns Hopkins Hospital (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-3027
- Citations
- 13
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 19.74