Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation

The combined oral minoxidil-finasteride regimen produced statistically significant and clinically meaningful improvements (p<0.001; N = 502) in AA over 12 months. The substantial proportion of stable/improved patients (92.4%, N = 464) and large effect sizes in severe stages highlight its potential. However, modest inter-rater reliability underscores the need for refined protocols or potential AI-driven evaluations. Future prospective trials should confirm these findings and explore optimal dosing, patient selection, and long-term durability.

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Publication Details

Journal
Cureus
Published
2025-01-16
DOI
https://doi.org/10.7759/cureus.77549
Citations
5
Primary Topic
Hair Growth and Disorders
Type
article
Field-Weighted Citation Impact
9.18
Controls
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article

Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation

Ashley Kieran Clift, Ângela Cristine Bersch-Ferreira, David T. Huang, Gustavo Cardoso Guimarães et al.
5 citations
Cureus
Hair Growth and Disorders
9.18
article

Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation

Ashley Kieran Clift, Ângela Cristine Bersch-Ferreira, David T. Huang, Gustavo Cardoso Guimarães, Hans Johnson
article en
5 citations

Abstract

The combined oral minoxidil-finasteride regimen produced statistically significant and clinically meaningful improvements (p<0.001; N = 502) in AA over 12 months. The substantial proportion of stable/improved patients (92.4%, N = 464) and large effect sizes in severe stages highlight its potential. However, modest inter-rater reliability underscores the need for refined protocols or potential AI-driven evaluations. Future prospective trials should confirm these findings and explore optimal dosing, patient selection, and long-term durability.

CureusVol. 17(1)
University of Bristol (GB), UK Research and Innovation (GB), Beneficência Portuguesa de São Paulo (BR), Imperial College London (GB), B. Braun (Netherlands) (NL)
Openalex Percentile: Top 3%
Hair Growth and Disorders
9.18
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