Effectiveness of Combined Oral Minoxidil and Finasteride in Male Androgenetic Alopecia: A Retrospective Service Evaluation
The combined oral minoxidil-finasteride regimen produced statistically significant and clinically meaningful improvements (p<0.001; N = 502) in AA over 12 months. The substantial proportion of stable/improved patients (92.4%, N = 464) and large effect sizes in severe stages highlight its potential. However, modest inter-rater reliability underscores the need for refined protocols or potential AI-driven evaluations. Future prospective trials should confirm these findings and explore optimal dosing, patient selection, and long-term durability.
Authors
- Ashley Kieran Clift (ORCID: https://orcid.org/0000-0002-0061-979X)
- Ângela Cristine Bersch-Ferreira (ORCID: https://orcid.org/0000-0003-3478-781X)
- David T. Huang (ORCID: https://orcid.org/0000-0002-8860-7469)
- Gustavo Cardoso Guimarães (ORCID: https://orcid.org/0000-0002-1317-2114)
- Hans Johnson
Institutions
- University of Bristol (GB)
- UK Research and Innovation (GB)
- Beneficência Portuguesa de São Paulo (BR)
- Imperial College London (GB)
- B. Braun (Netherlands) (NL)
Publication Details
- Journal
- Cureus
- Published
- 2025-01-16
- DOI
- https://doi.org/10.7759/cureus.77549
- Citations
- 5
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 9.18