Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)

HD white-light endoscopy with segmental re-inspection was non-inferior to HD chromoendoscopy for colorectal neoplasia detection in IBD patients. It can therefore be assumed that the benefit of HD chromoendoscopy may be explained by the longer withdrawal time and not necessarily the enhanced contrast. However, re-inspection per se did not lead to a significantly higher colorectal neoplasia rate than single-pass HD white-light endoscopy alone.

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Publication Details

Journal
Gut
Published
2025-01-16
DOI
https://doi.org/10.1136/gutjnl-2024-333446
Citations
10
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
18.17

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article

Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)

Charlotte P. Peters, Bas Oldenburg, Anouk M. Wijnands, Frank Hoentjen et al.
10 citations
Gut
Inflammatory Bowel Disease
18.17
article

Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)

Charlotte P. Peters, Bas Oldenburg, Anouk M. Wijnands, Frank Hoentjen, Andrea E. van der Meulen‐de Jong, Maarten te Groen, Philip W. Voorneveld, Willemijn A. van Dop, Dirk J. de Jong, Marjolijn Duijvestein, Nathan den Broeder, Jeroen Maljaars, Kimberly R. Boer, Herma H. Fidder, Meike M. Hirdes, Fiona van Schaik
article en
10 citations

Abstract

HD white-light endoscopy with segmental re-inspection was non-inferior to HD chromoendoscopy for colorectal neoplasia detection in IBD patients. It can therefore be assumed that the benefit of HD chromoendoscopy may be explained by the longer withdrawal time and not necessarily the enhanced contrast. However, re-inspection per se did not lead to a significantly higher colorectal neoplasia rate than single-pass HD white-light endoscopy alone.

GutVol. 74(4)
Radboud University Nijmegen (NL), University of Alberta (CA), Leiden University Medical Center (NL), Amsterdam UMC Location University of Amsterdam (NL), Radboud University Medical Center (NL), University Medical Center Utrecht (NL), Amsterdam University Medical Centers (NL), Vrije Universiteit Amsterdam (NL)
Teva Pharmaceutical Industries
Openalex Percentile: Top 1%
Inflammatory Bowel Disease
18.17
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