Dynamics of a Two‐Strain Model With Vaccination, General Incidence Rate, and Nonlocal Diffusion

ABSTRACT In this paper, we studied a two‐strain model with vaccination, general incidence rate, and nonlocal diffusion. In this model, it is considered that those vaccinated can become infected with either strain and that those removed individuals with respect to strain 1 can become infected with strain 2 (partial cross‐immunity). We prove that solution exists and is unique, bounded, and positive, and there exists a disease‐free steady state. The basic reproduction number is defined, and the existence of principal eigenvalue is studied. For , we prove the disease‐free steady state is globally asymptotically stable, and when , the disease‐free steady state is unstable. We also prove the uniform persistence of the system. Four steady states were obtained, and it was shown that the existence of each of the steady state depends on 4 threshold quantities and we used a Lyapunov approach to prove the global stability of the steady state under certain assumptions. The results are confirmed using some graphical representations.

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Publication Details

Journal
Mathematical Methods in the Applied Sciences
Published
2025-01-16
DOI
https://doi.org/10.1002/mma.10680
Primary Topic
Mathematical and Theoretical Epidemiology and Ecology Models
Type
article
Field-Weighted Citation Impact
0.00

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article

Dynamics of a Two‐Strain Model With Vaccination, General Incidence Rate, and Nonlocal Diffusion

Arturo J. Nic‐May, Eric Ávila-Vales
Mathematical Methods in the Applied Sciences
Mathematical and Theoretical Epidemiology and Ecology Models
article

Dynamics of a Two‐Strain Model With Vaccination, General Incidence Rate, and Nonlocal Diffusion

Arturo J. Nic‐May, Eric Ávila-Vales
article en

Abstract

ABSTRACT In this paper, we studied a two‐strain model with vaccination, general incidence rate, and nonlocal diffusion. In this model, it is considered that those vaccinated can become infected with either strain and that those removed individuals with respect to strain 1 can become infected with strain 2 (partial cross‐immunity). We prove that solution exists and is unique, bounded, and positive, and there exists a disease‐free steady state. The basic reproduction number is defined, and the existence of principal eigenvalue is studied. For , we prove the disease‐free steady state is globally asymptotically stable, and when , the disease‐free steady state is unstable. We also prove the uniform persistence of the system. Four steady states were obtained, and it was shown that the existence of each of the steady state depends on 4 threshold quantities and we used a Lyapunov approach to prove the global stability of the steady state under certain assumptions. The results are confirmed using some graphical representations.

Mathematical Methods in the Applied SciencesVol. 48(6)
Autonomous University of Yucatán (MX)
Consejo Nacional de Ciencia y Tecnología, Sistema Nacional de Investigadores
Openalex Percentile: Top 99%
Mathematical and Theoretical Epidemiology and Ecology Models
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