Uji efektivitas ekstrak kulit buah mahoni (swietenia mahagoni l.) terhadap bakteri salmonella thyphi

Background:Typhoid fever is a disease that arises due to infection with pathogenic bacteria such as Salmonella typhi. The plant commonly used by the community to cure typhoid fever is by using mahogany fruit skin. Purpose: To identify the effectiveness of mahogany rind extract as an antibacterial against Salmonella typhi bacteria and determine the concentration of mahogany rind extract against Salmonella typhi bacteria. Methods: This study used the soxhlet extraction method with 96 percent ethanol as solvent. Results: The effectiveness obtained from the mahogany rind extract test (Swietenia mahagoni L) was 29.6 percent, the extraction result was 6.7 percent, the phytochemical screening results of the mahogany rind extract obtained flavonoid compounds, saponins, phenolics, tannins and alkaloids. The results of the effectiveness of mahogany skin extract (Switenia mahagoni L) was effective at a concentration of 10 percent with an inhibition zone of 8.5 mm which had a moderate inhibitory response. Conclusion: Ethanol extract of mahogany peel (Switenia mahagoni L) has properties that can inhibit the geowth of Salmonella typhi bacteria. Keywords: Effectiveness; Mahogany Fruit Peel Extract (Swietenia Mahagoni L.); Salmonella Typii. Pendahuluan: Demam tifoid adalah salah satu penyakit yang timbul akibat infeksi bakteri patogen seperti bakteri Salmonella typhi.tanaman yang biasa digunakan oleh masyarakat untuk menyembuhkan demam tifoid yaitu dengan menggunakan kulit buah mahoni. Tujuan: Untuk mengidentifikasi efektivitas ekstrak kulit buah mahoni sebagai antibakteri pada bakteri Salmonella typhi dan menentukan konsentrasi ekstrak kulit buah mahoni terhadap bakteri Salmonella typhi. Metode: Penelitian ini menggunakan metode ekstraksi sokletasi dengan pelarut etanol 96 persen. Hasil: Efektivitas yang diperoleh dari uji ekstrak kulit buah mahoni (Swietenia mahagoni L) yaitu 29,6 persen,Hasil ekstraksi diperoleh 6,7 persen, pada hasil skrining fitokimia ekstrak kulit buah mahoni diperoleh senyawa flavonoid, saponin, fenolik, tanin dan alkaloid. Hasil efektivitas ekstrak kulit buah mahoni (Switenia mahagoni L) sudah efektiv pada konsentrasi 10 persen dengan zona hambat 8,5 mm yang memiliki respon hambat sedang. Simpulan: Ekstrak etanol kulit buah mahoni (Swietenia mahagoni L) memiliki sifat yang dapat menghambat pertumbuhan bakteri Salmonella typhi. Kata Kunci: Efektivitas; Ekstrak Kulit Buah Mahoni (Swietenia Mahagoni L.); Salmonella Thypi.

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Journal
JOURNAL OF Pharmacy and Tropical Issues
Published
2024-12-12
DOI
https://doi.org/10.56922/pti.v4i2.536
Primary Topic
Plant Growth and Agriculture Techniques
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article
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article

Uji efektivitas ekstrak kulit buah mahoni (swietenia mahagoni l.) terhadap bakteri salmonella thyphi

Tutik Tutik, Selvi Marcellia, Mariska Mulya Safitri
JOURNAL OF Pharmacy and Tropical Issues
Plant Growth and Agriculture Techniques
article

Uji efektivitas ekstrak kulit buah mahoni (swietenia mahagoni l.) terhadap bakteri salmonella thyphi

Tutik Tutik, Selvi Marcellia, Mariska Mulya Safitri
article en

Abstract

Background:Typhoid fever is a disease that arises due to infection with pathogenic bacteria such as Salmonella typhi. The plant commonly used by the community to cure typhoid fever is by using mahogany fruit skin. Purpose: To identify the effectiveness of mahogany rind extract as an antibacterial against Salmonella typhi bacteria and determine the concentration of mahogany rind extract against Salmonella typhi bacteria. Methods: This study used the soxhlet extraction method with 96 percent ethanol as solvent. Results: The effectiveness obtained from the mahogany rind extract test (Swietenia mahagoni L) was 29.6 percent, the extraction result was 6.7 percent, the phytochemical screening results of the mahogany rind extract obtained flavonoid compounds, saponins, phenolics, tannins and alkaloids. The results of the effectiveness of mahogany skin extract (Switenia mahagoni L) was effective at a concentration of 10 percent with an inhibition zone of 8.5 mm which had a moderate inhibitory response. Conclusion: Ethanol extract of mahogany peel (Switenia mahagoni L) has properties that can inhibit the geowth of Salmonella typhi bacteria. Keywords: Effectiveness; Mahogany Fruit Peel Extract (Swietenia Mahagoni L.); Salmonella Typii. Pendahuluan: Demam tifoid adalah salah satu penyakit yang timbul akibat infeksi bakteri patogen seperti bakteri Salmonella typhi.tanaman yang biasa digunakan oleh masyarakat untuk menyembuhkan demam tifoid yaitu dengan menggunakan kulit buah mahoni. Tujuan: Untuk mengidentifikasi efektivitas ekstrak kulit buah mahoni sebagai antibakteri pada bakteri Salmonella typhi dan menentukan konsentrasi ekstrak kulit buah mahoni terhadap bakteri Salmonella typhi. Metode: Penelitian ini menggunakan metode ekstraksi sokletasi dengan pelarut etanol 96 persen. Hasil: Efektivitas yang diperoleh dari uji ekstrak kulit buah mahoni (Swietenia mahagoni L) yaitu 29,6 persen,Hasil ekstraksi diperoleh 6,7 persen, pada hasil skrining fitokimia ekstrak kulit buah mahoni diperoleh senyawa flavonoid, saponin, fenolik, tanin dan alkaloid. Hasil efektivitas ekstrak kulit buah mahoni (Switenia mahagoni L) sudah efektiv pada konsentrasi 10 persen dengan zona hambat 8,5 mm yang memiliki respon hambat sedang. Simpulan: Ekstrak etanol kulit buah mahoni (Swietenia mahagoni L) memiliki sifat yang dapat menghambat pertumbuhan bakteri Salmonella typhi. Kata Kunci: Efektivitas; Ekstrak Kulit Buah Mahoni (Swietenia Mahagoni L.); Salmonella Thypi.

JOURNAL OF Pharmacy and Tropical IssuesVol. 4(2)
Lampung University (ID), Universitas Malahayati (ID)
Openalex Percentile: Top 65%
Plant Growth and Agriculture Techniques
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