Exploring the phytochemical constituents of Plumeria obtusa L. root and stem extracts through GC-MS analysis

This study investigates the bioactive phytochemicals present in the root and stem extracts of Plumeria obtusa L., commonly known as the 'Great white frangipani' using gas chromatography-mass spectrometry (GC-MS).Traditionally used in various medicinal applications, P. obtusa is valued for its therapeutic properties.The GC-MS analysis identified a wide array of bioactive compounds, including ethyl alpha-dglucopyranoside, 2,3-dihydrobenzofuran, n-decanoic acid and methyl beta-d-glucopyranoside.These compounds exhibit significant pharmacological activities such as antioxidant, anticancer, antimicrobial and anti-inflammatory effects.Glycosides like ethyl alpha-d-glucopyranoside and methyl beta-dglucopyranoside showed strong antioxidant and skin-moisturizing properties, indicating their potential for pharmaceutical and cosmetic applications.Fatty acids such as n-decanoic acid and methyl palmitate displayed anti-inflammatory and antimicrobial properties, making them suitable for treating infections and inflammation related conditions.Additionally, plumericin, a terpenoid, demonstrated potent antibacterial, antifungal and antiviral properties, while 9,12-octadecadienoic acid methyl ester showed promise as an analgesic and anticancer agent.The study highlights the potential of P. obtusa extracts for applications in pharmaceuticals, cosmetics and agriculture.The findings underscore the need for further research to explore the therapeutic potential of these bioactive compounds and to develop new applications in various industries.

Authors

Publication Details

Journal
Annals of Phytomedicine An International Journal
Published
2024-12-01
DOI
https://doi.org/10.54085/ap.2024.13.2.84
Primary Topic
Phytochemistry and Biological Activities
Type
article
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article

Exploring the phytochemical constituents of Plumeria obtusa L. root and stem extracts through GC-MS analysis

N. Sritharan, S. P. Thamaraiselvi, P. Malathi, M Ganga et al.
Annals of Phytomedicine An International Journal
Phytochemistry and Biological Activities
article

Exploring the phytochemical constituents of Plumeria obtusa L. root and stem extracts through GC-MS analysis

N. Sritharan, S. P. Thamaraiselvi, P. Malathi, M Ganga, J. Jaahnavi
article en

Abstract

This study investigates the bioactive phytochemicals present in the root and stem extracts of Plumeria obtusa L., commonly known as the 'Great white frangipani' using gas chromatography-mass spectrometry (GC-MS).Traditionally used in various medicinal applications, P. obtusa is valued for its therapeutic properties.The GC-MS analysis identified a wide array of bioactive compounds, including ethyl alpha-dglucopyranoside, 2,3-dihydrobenzofuran, n-decanoic acid and methyl beta-d-glucopyranoside.These compounds exhibit significant pharmacological activities such as antioxidant, anticancer, antimicrobial and anti-inflammatory effects.Glycosides like ethyl alpha-d-glucopyranoside and methyl beta-dglucopyranoside showed strong antioxidant and skin-moisturizing properties, indicating their potential for pharmaceutical and cosmetic applications.Fatty acids such as n-decanoic acid and methyl palmitate displayed anti-inflammatory and antimicrobial properties, making them suitable for treating infections and inflammation related conditions.Additionally, plumericin, a terpenoid, demonstrated potent antibacterial, antifungal and antiviral properties, while 9,12-octadecadienoic acid methyl ester showed promise as an analgesic and anticancer agent.The study highlights the potential of P. obtusa extracts for applications in pharmaceuticals, cosmetics and agriculture.The findings underscore the need for further research to explore the therapeutic potential of these bioactive compounds and to develop new applications in various industries.

Annals of Phytomedicine An International JournalVol. 13(2)
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Openalex Percentile: Top 85%
Phytochemistry and Biological Activities
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Exploring the phytochemical constituents of Plumeria obtusa L. root and stem extracts through GC-MS analysis — N. Sritharan, S. P. Thamaraiselvi, et al. · Annals of Phytomedicine An International Journal (2024) | TGRS Research Map | TGRS