Exploring the phytochemical constituents of Plumeria obtusa L. root and stem extracts through GC-MS analysis
This study investigates the bioactive phytochemicals present in the root and stem extracts of Plumeria obtusa L., commonly known as the 'Great white frangipani' using gas chromatography-mass spectrometry (GC-MS).Traditionally used in various medicinal applications, P. obtusa is valued for its therapeutic properties.The GC-MS analysis identified a wide array of bioactive compounds, including ethyl alpha-dglucopyranoside, 2,3-dihydrobenzofuran, n-decanoic acid and methyl beta-d-glucopyranoside.These compounds exhibit significant pharmacological activities such as antioxidant, anticancer, antimicrobial and anti-inflammatory effects.Glycosides like ethyl alpha-d-glucopyranoside and methyl beta-dglucopyranoside showed strong antioxidant and skin-moisturizing properties, indicating their potential for pharmaceutical and cosmetic applications.Fatty acids such as n-decanoic acid and methyl palmitate displayed anti-inflammatory and antimicrobial properties, making them suitable for treating infections and inflammation related conditions.Additionally, plumericin, a terpenoid, demonstrated potent antibacterial, antifungal and antiviral properties, while 9,12-octadecadienoic acid methyl ester showed promise as an analgesic and anticancer agent.The study highlights the potential of P. obtusa extracts for applications in pharmaceuticals, cosmetics and agriculture.The findings underscore the need for further research to explore the therapeutic potential of these bioactive compounds and to develop new applications in various industries.
Authors
- N. Sritharan (ORCID: https://orcid.org/0000-0002-4016-7281)
- S. P. Thamaraiselvi (ORCID: https://orcid.org/0000-0002-0070-4206)
- P. Malathi (ORCID: https://orcid.org/0000-0002-6781-6720)
- M Ganga (ORCID: https://orcid.org/0000-0002-7525-2849)
- J. Jaahnavi
Publication Details
- Journal
- Annals of Phytomedicine An International Journal
- Published
- 2024-12-01
- DOI
- https://doi.org/10.54085/ap.2024.13.2.84
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00