GC-MS profiling of bioactive compounds in methanolic extract of Aloe barbadensis Mill. and their therapeutic potential

This study examined the phytochemical compounds found in a methanolic extract of Aloe barbadensis Mill.leaves through the use of GC-MS.The researchers aimed to profile these compounds and discuss their potential therapeutic applications, given Aloe vera (A.vera) widespread use in traditional medicine.Fresh aloe leaves were harvested, dried, powdered, and extracted using methanol in a Soxhlet apparatus.The extract was analyzed with Gas chromatography and mass spectroscopy (GC-MS), with compounds identified by matching their mass spectra to the NIST library.The examination uncovered various important bioactive chemicals, such as -sitosterol (14.41%), n-hexadecanoic acid (2.33%), 2-furancarboxaldehyde, 5-(hydroxymethyl)-(5.87%), and squalene (2.93%).These compounds are known to possess different advantageous properties, including anti-inflammatory, anticancer, and antioxidant effects.The discovery of these substances offers scientific backing for the traditional benefits of A. vera and showcases its potential medical uses.