Treadmill Exercise Mitigates Alzheimer’s Pathology by Modulating Glial Polarization and Reducing Oligodendrocyte Precursor Cell Perivascular Clustering
Exercise can counteract AD pathological features by modulating glial responses and reducing OPC senescence and perivascular clustering near amyloid plaques, highlighting its potential as a therapeutic strategy for AD.
Authors
- Rui Duan (ORCID: https://orcid.org/0000-0001-5035-5633)
- Ling Zhu (ORCID: https://orcid.org/0000-0002-6559-0967)
- Peibin Zou
- Timon Cheng‐Yi Liu (ORCID: https://orcid.org/0000-0002-6585-1776)
- Shu Feng
- Luodan Yang (ORCID: https://orcid.org/0000-0002-5671-3750)
- Chongyun Wu
- Qianting Deng
Institutions
- U.S. National Science Foundation (US)
- South China Normal University (CN)
Publication Details
- Journal
- Medicine & Science in Sports & Exercise
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1249/mss.0000000000003650
- Citations
- 10
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 11.64