Durable and Drastic Response to the Trastuzumab, Letrozole, Abemaciclib, and Goserelin Combination as First-Line Therapy in HER2-Positive and Hormone Receptor-Positive Metastatic Breast Cancer: A Case Report

We believe that the combination of trastuzumab, hormone suppression, and abemaciclib is a practicable and effective treatment for HER2-positive and HR-positive metastatic BC in premenopausal patients who cannot tolerate the first-line chemotherapy.

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Publication Details

Journal
Case Reports in Oncology
Published
2025-01-16
DOI
https://doi.org/10.1159/000542926
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
0.00

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article

Durable and Drastic Response to the Trastuzumab, Letrozole, Abemaciclib, and Goserelin Combination as First-Line Therapy in HER2-Positive and Hormone Receptor-Positive Metastatic Breast Cancer: A Case Report

Siwanon Jirawatnotai, Ployploen Phikulsod, Harit Suwanrusme, Suthida Suwanvecho et al.
Case Reports in Oncology
Advanced Breast Cancer Therapies
article

Durable and Drastic Response to the Trastuzumab, Letrozole, Abemaciclib, and Goserelin Combination as First-Line Therapy in HER2-Positive and Hormone Receptor-Positive Metastatic Breast Cancer: A Case Report

Siwanon Jirawatnotai, Ployploen Phikulsod, Harit Suwanrusme, Suthida Suwanvecho, Narongsak Kiatikajornthada
article en

Abstract

We believe that the combination of trastuzumab, hormone suppression, and abemaciclib is a practicable and effective treatment for HER2-positive and HR-positive metastatic BC in premenopausal patients who cannot tolerate the first-line chemotherapy.

Case Reports in OncologyVol. 18(1)
Siriraj Hospital (TH), Mahidol University (TH), Bumrungrad International Hospital (TH)
Mahidol University, National Research Council of Thailand, Faculty of Medicine Siriraj Hospital, Mahidol University
Good health and well-being
Openalex Percentile: Top 99%
Advanced Breast Cancer Therapies
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Durable and Drastic Response to the Trastuzumab, Letrozole, Abemaciclib, and Goserelin Combination as First-Line Therapy in HER2-Positive and Hormone Receptor-Positive Metastatic Breast Cancer: A Case Report — Siwanon Jirawatnotai, Ployploen Phikulsod, et al. · Case Reports in Oncology (2025) | TGRS Research Map | TGRS