Exploring Azithromycin’s Neuroprotective Role in Traumatic Brain Injury: Insights into Cognitive and Motor Recovery and Neuroinflammatory Modulation
AZI was shown to interfere with several pathways involved in TBI's pathophysiology. While preclinical results are promising, further studies are necessary to establish the long-term safety and efficacy of AZI in a clinical setting. This research supports the potential re-purposing of AZI as a novel treatment strategy for TBI and related neurodegenerative disorders.
Authors
- Zuber Khan (ORCID: https://orcid.org/0000-0002-0887-754X)
- Nehad A. Abdallah (ORCID: https://orcid.org/0000-0001-5662-2173)
- Tahani A. Saeedi (ORCID: https://orcid.org/0009-0009-0941-9696)
- Hanaa Wanas (ORCID: https://orcid.org/0000-0002-7109-939X)
- Haifa Abdulrahman Fadil (ORCID: https://orcid.org/0000-0003-3123-0127)
- Sultan S. Althagfan (ORCID: https://orcid.org/0000-0003-0144-9021)
- Sidharth Mehan (ORCID: https://orcid.org/0000-0003-0034-835X)
- Ahmed Aldhafiri (ORCID: https://orcid.org/0000-0003-3127-6299)
- Ahmed K. B. Aljohani (ORCID: https://orcid.org/0000-0003-2332-1125)
- Hossein Mostafa Elbadawy (ORCID: https://orcid.org/0000-0001-8675-0838)
- Mohannad A. Almikhlafi (ORCID: https://orcid.org/0000-0002-4499-8605)
- Sara A. Almadani (ORCID: https://orcid.org/0000-0003-1791-6480)
- Aakash Kumar (ORCID: https://orcid.org/0009-0003-6879-2104)
- Tarun Sharma
- Samar F. Miski
- Abdulrahman M. Alharthe
- Rayan S. Alharbi
- Mohammed H. Alsubhi
Institutions
- Cairo University (EG)
- Taibah University (SA)
- Punjab Technical University (IN)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2025-01-16
- DOI
- https://doi.org/10.3390/ph18010115
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- King Salman Center for Disability Research