Woxuanzhongzhou formula improves DHEAS and high-fat diet-induced IR and anovulatory mice via AMPK/PGC1- α/Irisin pathway
WXZZ exhibits therapeutic effects in DHEAS and high-fat diet-induced IR and anovulatory mice. These effects may be mediated through the activation of AMPK/PGC1-α pathway in muscle to promote the secretion of irisin.
Authors
- Xiang-Yu He (ORCID: https://orcid.org/0000-0001-8115-3727)
- Conglu Sui
- Haijuan Liu
- Guohua Wang (ORCID: https://orcid.org/0000-0002-4810-8534)
- Yanan Guo (ORCID: https://orcid.org/0000-0001-8592-6993)
Institutions
- Beijing University of Chinese Medicine (CN)
- Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital (CN)
- Northwest Women's and Children's Hospital (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-01-16
- DOI
- https://doi.org/10.1186/s13048-025-01587-5
- Citations
- 5
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 5.82
Funders
- Beijing University of Chinese Medicine