A cycle of complications: a case report on trastuzumab-induced takotsubo cardiomyopathy causing left ventricular thrombosis complicated by thromboembolic stroke

This case highlights TC and LVT as rare but life-threatening complications of trastuzumab-induced cardiotoxicity. We emphasize the importance of early diagnosis to prevent further complications, such as acute thromboembolic stroke, and the necessity of prompt therapeutic interventions to reduce morbidity and mortality. Additionally, we address the multifactorial aetiology of TC and the need for frequent TTE monitoring in patients undergoing trastuzumab therapy to diagnose these complications early.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-01-16
DOI
https://doi.org/10.1093/ehjcr/ytaf002
Citations
1
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
Field-Weighted Citation Impact
1.39
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article

A cycle of complications: a case report on trastuzumab-induced takotsubo cardiomyopathy causing left ventricular thrombosis complicated by thromboembolic stroke

Tetyana Okan, J. Yee, Vidhi Patel, Jagruti Patel
1 citations
European Heart Journal - Case Reports
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
article

A cycle of complications: a case report on trastuzumab-induced takotsubo cardiomyopathy causing left ventricular thrombosis complicated by thromboembolic stroke

Tetyana Okan, J. Yee, Vidhi Patel, Jagruti Patel
article en
1 citations

Abstract

This case highlights TC and LVT as rare but life-threatening complications of trastuzumab-induced cardiotoxicity. We emphasize the importance of early diagnosis to prevent further complications, such as acute thromboembolic stroke, and the necessity of prompt therapeutic interventions to reduce morbidity and mortality. Additionally, we address the multifactorial aetiology of TC and the need for frequent TTE monitoring in patients undergoing trastuzumab therapy to diagnose these complications early.

European Heart Journal - Case ReportsVol. 9(2)
Jamaica Hospital (US)
Openalex Percentile: Top 24%
Takotsubo Cardiomyopathy and Associated Phenomena
1.39
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